Products > Assay Platform > The DiagnostIQ™
The DiagnostIQ™
- Vertical flow assay
- Rapid and quantifiable
- Increased sensitivity with integrated pre-incubation
- Particulate samples do not cause flow problems
DCN can assist you in securing a license to this patented technology and develop assays on the system for you
Lateral Flow Immunoassay (LFIA) is not the only potential format for point of need membrane based diagnostics. Other formats, such as flow through assays may have advantages, particularly in assays that demand difficult sample processing, high sensitivity and quantification.
Flow Through Assays
In flow through systems, a membrane is still used as a reaction matrix, onto which capture and control lines of proteins or oligonucleotides are striped. In the flow through system, however, the remaining reagents – sample, wash buffers and conjugates – pass vertically through the membrane and are captured in an absorbent wick beneath the membrane.
Advantages and Disadvantages of Flow Through systems
Flow through assays can be more sensitive and less variable than LFIA’s, while utilizing the same labeling and reading technologies. This format also has a significantly cleaner patent environment, allowing for an easier path to market. The drawback has been that traditionally, the user had to perform multiple steps to run the assay, rather than a single addition, as in a typical LFIA. This issue can, however, be overcome using the DiagnostIQ™ platform.
The DiagnostIQ™ is a vertical flow assay system that possesses several novel elements, including a proprietary pre-incubation chamber and filtration area, where the conjugate can be pre-mixed with the sample and thereafter filtered onto the membrane. There the reactants are captured by pre-striped capture and control lines. DCN offers assay development services and can arrange development licenses for third parties wishing to develop assays on this device.
Operation of The DiagnostIQ™
Result Interpretation and Application
The DiagnostIQ can be interpreted by eye or using a proprietary integrated reader system. DCN can integrate this reader to your assay to generate highly quantitative assays with frequently better reproducibility that lateral flow.
For more information click on the link below:
DiagnostIQ Application Sheet